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SMILES: Cn1c2cccc(C(=O)Nc3cccc(Cl)c3)c2[nH]c1=O

InChI Key: InChIKey=DFLKLKBRKRRZGG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201487   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50201487
PNG
(CHEMBL239600 | N-(3-chlorophenyl)-1-methyl-2-oxo-2...)
Show SMILES Cn1c2cccc(C(=O)Nc3cccc(Cl)c3)c2[nH]c1=O
Show InChI InChI=1S/C15H12ClN3O2/c1-19-12-7-3-6-11(13(12)18-15(19)21)14(20)17-10-5-2-4-9(16)8-10/h2-8H,1H3,(H,17,20)(H,18,21)
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KEGG

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Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Binding affinity to mGluR5

Bioorg Med Chem Lett 17: 1302-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.006
BindingDB Entry DOI: 10.7270/Q2H41R3G
More data for this
Ligand-Target Pair