Found 4 hits for monomerid = 50201697 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase SYK
(Homo sapiens (Human)) | BDBM50201697
(CHEMBL3943181)Show SMILES N[C@H]1CCCC[C@H]1Nc1cnc(C(N)=O)c(n1)-c1nc2ccccc2[nH]1 |r| Show InChI InChI=1S/C18H21N7O/c19-10-5-1-2-6-11(10)22-14-9-21-15(17(20)26)16(25-14)18-23-12-7-3-4-8-13(12)24-18/h3-4,7-11H,1-2,5-6,19H2,(H2,20,26)(H,22,25)(H,23,24)/t10-,11+/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged full length human SYK (1 to 635 end residues) expressed in baculovirus expression system preincubated for 10 mins followed b... |
ACS Med Chem Lett 7: 1151-1155 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00353
BindingDB Entry DOI: 10.7270/Q2FB54XR |
More data for this
Ligand-Target Pair | |
Testis-specific serine/threonine-protein kinase 3
(Homo sapiens (Human)) | BDBM50201697
(CHEMBL3943181)Show SMILES N[C@H]1CCCC[C@H]1Nc1cnc(C(N)=O)c(n1)-c1nc2ccccc2[nH]1 |r| Show InChI InChI=1S/C18H21N7O/c19-10-5-1-2-6-11(10)22-14-9-21-15(17(20)26)16(25-14)18-23-12-7-3-4-8-13(12)24-18/h3-4,7-11H,1-2,5-6,19H2,(H2,20,26)(H,22,25)(H,23,24)/t10-,11+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of TSSK3 (unknown origin) |
ACS Med Chem Lett 7: 1151-1155 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00353
BindingDB Entry DOI: 10.7270/Q2FB54XR |
More data for this
Ligand-Target Pair | |
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)
(Homo sapiens (Human)) | BDBM50201697
(CHEMBL3943181)Show SMILES N[C@H]1CCCC[C@H]1Nc1cnc(C(N)=O)c(n1)-c1nc2ccccc2[nH]1 |r| Show InChI InChI=1S/C18H21N7O/c19-10-5-1-2-6-11(10)22-14-9-21-15(17(20)26)16(25-14)18-23-12-7-3-4-8-13(12)24-18/h3-4,7-11H,1-2,5-6,19H2,(H2,20,26)(H,22,25)(H,23,24)/t10-,11+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of GST-tagged recombinant human LRRK2 (970 to 2527 residues) expressed in baculovirus |
ACS Med Chem Lett 7: 1151-1155 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00353
BindingDB Entry DOI: 10.7270/Q2FB54XR |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase Chk2
(Homo sapiens (Human)) | BDBM50201697
(CHEMBL3943181)Show SMILES N[C@H]1CCCC[C@H]1Nc1cnc(C(N)=O)c(n1)-c1nc2ccccc2[nH]1 |r| Show InChI InChI=1S/C18H21N7O/c19-10-5-1-2-6-11(10)22-14-9-21-15(17(20)26)16(25-14)18-23-12-7-3-4-8-13(12)24-18/h3-4,7-11H,1-2,5-6,19H2,(H2,20,26)(H,22,25)(H,23,24)/t10-,11+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of His-tagged recombinant full length human CHK2 expressed in baculovirus |
ACS Med Chem Lett 7: 1151-1155 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00353
BindingDB Entry DOI: 10.7270/Q2FB54XR |
More data for this
Ligand-Target Pair | |
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