BDBM50201702 (1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane-6-thione::CHEMBL390643
SMILES: S=C1O[C@@H]2CN1CC[C@@H]2Oc1ccccc1
InChI Key: InChIKey=BMIOGAIQRVIVKQ-WDEREUQCSA-N
Data: 9 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase I (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 606 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin C | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin K (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin K | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pro-cathepsin H (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin H | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 994 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin L | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 519 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin B | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin F (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin F | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin S (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 696 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin S | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin K (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin X | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin L2 (Homo sapiens (Human)) | BDBM50201702 ((1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin V | Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT | |||||||||||
More data for this Ligand-Target Pair |