BDBM50201707 5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin-2-one::CHEMBL397973

SMILES: CN1CC(COc2cccc(C)c2C)OC1=O

InChI Key: InChIKey=UWNKJJCNLMBGKB-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-cathepsin H (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin H				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin X				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Dipeptidyl peptidase I (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin F (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin F				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin S				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin B				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin L				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin L2 (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin V				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50201707 (5-((2,3-dimethylphenoxy)methyl)-3-methyloxazolidin...) Show SMILES CN1CC(COc2cccc(C)c2C)OC1=O |w:3.3| Show InChI InChI=1S/C13H17NO3/c1-9-5-4-6-12(10(9)2)16-8-11-7-14(3)13(15)17-11/h4-6,11H,7-8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin K				Bioorg Med Chem Lett 17: 1254-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.014 BindingDB Entry DOI: 10.7270/Q2QN66DT
					More data for this Ligand-Target Pair