BDBM50201766 CHEMBL3931691
SMILES: CCc1ccc(cc1)-c1cc(ncn1)C(=O)Nc1ccc(Oc2ccnc(c2)C(=O)NC)cc1
InChI Key: InChIKey=MKLJTOUVMDMWOT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50201766 (CHEMBL3931691) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangxi Science& Technology Normal University Curated by ChEMBL | Assay Description Inhibition of VEGFR2 (unknown origin) by mobility shift/LanthaScreen assay | Bioorg Med Chem 24: 6166-6173 (2016) Article DOI: 10.1016/j.bmc.2016.09.021 BindingDB Entry DOI: 10.7270/Q2XD13PQ | |||||||||||
More data for this Ligand-Target Pair |