BDBM50201803 CHEMBL3908947

SMILES: CCOC(=O)c1c(C)[nH]c(\C=C2/S\C(=N\O)N(C(C)C)C2=O)c1C

InChI Key: InChIKey=GDWDTFHKYWLYHH-JKUQNHOPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50201803 (CHEMBL3908947) Show SMILES CCOC(=O)c1c(C)[nH]c(\C=C2/S\C(=N\O)N(C(C)C)C2=O)c1C Show InChI InChI=1S/C16H21N3O4S/c1-6-23-15(21)13-9(4)11(17-10(13)5)7-12-14(20)19(8(2)3)16(18-22)24-12/h7-8,17,22H,6H2,1-5H3/b12-7-,18-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CDC25B assessed as reduction in dephosphorylation of florigenic phosphatase substrate preincubated for 1 h...				Eur J Med Chem 122: 756-769 (2016) Article DOI: 10.1016/j.ejmech.2016.05.060 BindingDB Entry DOI: 10.7270/Q25Q4Z2D
					More data for this Ligand-Target Pair