BDBM50201895 8-chloro-2-(4-chlorophenyl)-3-hydroxyquinoline-4-carboxylicacid::CHEMBL384543

SMILES: OC(=O)c1c(O)c(nc2c(Cl)cccc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=CXLWGHIVYZAREC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50201895 (8-chloro-2-(4-chlorophenyl)-3-hydroxyquinoline-4-c...) Show SMILES OC(=O)c1c(O)c(nc2c(Cl)cccc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H9Cl2NO3/c17-9-6-4-8(5-7-9)13-15(20)12(16(21)22)10-2-1-3-11(18)14(10)19-13/h1-7,20H,(H,21,22)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of P-selectin-mediated adhesion of HL60 cells				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM50201895 (8-chloro-2-(4-chlorophenyl)-3-hydroxyquinoline-4-c...) Show SMILES OC(=O)c1c(O)c(nc2c(Cl)cccc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H9Cl2NO3/c17-9-6-4-8(5-7-9)13-15(20)12(16(21)22)10-2-1-3-11(18)14(10)19-13/h1-7,20H,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant DHOD expressed in Escherichia coli				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair