BDBM50201899 2-(4-chlorophenyl)-8-ethyl-3-hydroxyquinoline-4-carboxylicacid::CHEMBL373494

SMILES: CCc1cccc2c(C(O)=O)c(O)c(nc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=LAGVLCJPVMUVGT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50201899 (2-(4-chlorophenyl)-8-ethyl-3-hydroxyquinoline-4-ca...) Show SMILES CCc1cccc2c(C(O)=O)c(O)c(nc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H14ClNO3/c1-2-10-4-3-5-13-14(18(22)23)17(21)16(20-15(10)13)11-6-8-12(19)9-7-11/h3-9,21H,2H2,1H3,(H,22,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of P-selectin-mediated adhesion of HL60 cells				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair