BDBM50201906 2-(4-chlorophenyl)-3-hydroxy-8-methyl-6-(trifluoromethoxy)-quinoline-4-carboxylic acid::CHEMBL219697

SMILES: Cc1cc(OC(F)(F)F)cc2c(C(O)=O)c(O)c(nc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=WABHKXJPFKVJKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50201906 (2-(4-chlorophenyl)-3-hydroxy-8-methyl-6-(trifluoro...) Show SMILES Cc1cc(OC(F)(F)F)cc2c(C(O)=O)c(O)c(nc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H11ClF3NO4/c1-8-6-11(27-18(20,21)22)7-12-13(17(25)26)16(24)15(23-14(8)12)9-2-4-10(19)5-3-9/h2-7,24H,1H3,(H,25,26)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of P-selectin-mediated adhesion of HL60 cells				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair