BDBM50201908 2-(4-chlorophenyl)-3-hydroxy-7-phenylquinoline-4-carboxylicacid::CHEMBL218584

SMILES: OC(=O)c1c(O)c(nc2cc(ccc12)-c1ccccc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=NFSOHDQDQSYZTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50201908 (2-(4-chlorophenyl)-3-hydroxy-7-phenylquinoline-4-c...) Show SMILES OC(=O)c1c(O)c(nc2cc(ccc12)-c1ccccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H14ClNO3/c23-16-9-6-14(7-10-16)20-21(25)19(22(26)27)17-11-8-15(12-18(17)24-20)13-4-2-1-3-5-13/h1-12,25H,(H,26,27)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of P-selectin-mediated adhesion of HL60 cells				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair