BDBM50201913 2-(4-chlorophenyl)-3-hydroxy-6-(trifluoromethyl)quinoline-4-carboxylic acid::CHEMBL386700

SMILES: OC(=O)c1c(O)c(nc2ccc(cc12)C(F)(F)F)-c1ccc(Cl)cc1

InChI Key: InChIKey=VKXYBRPZHFQWGP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM50201913 (2-(4-chlorophenyl)-3-hydroxy-6-(trifluoromethyl)qu...) Show SMILES OC(=O)c1c(O)c(nc2ccc(cc12)C(F)(F)F)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H9ClF3NO3/c18-10-4-1-8(2-5-10)14-15(23)13(16(24)25)11-7-9(17(19,20)21)3-6-12(11)22-14/h1-7,23H,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant DHOD expressed in Escherichia coli				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50201913 (2-(4-chlorophenyl)-3-hydroxy-6-(trifluoromethyl)qu...) Show SMILES OC(=O)c1c(O)c(nc2ccc(cc12)C(F)(F)F)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H9ClF3NO3/c18-10-4-1-8(2-5-10)14-15(23)13(16(24)25)11-7-9(17(19,20)21)3-6-12(11)22-14/h1-7,23H,(H,24,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of P-selectin-mediated adhesion of HL60 cells				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair