BDBM50201920 2-(4-chlorophenyl)-3-hydroxy-6,8-dimethylquinoline-4-carboxylicacid::CHEMBL375425

SMILES: Cc1cc(C)c2nc(c(O)c(C(O)=O)c2c1)-c1ccc(Cl)cc1

InChI Key: InChIKey=WYFYAZDPFHWPCD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM50201920 (2-(4-chlorophenyl)-3-hydroxy-6,8-dimethylquinoline...) Show SMILES Cc1cc(C)c2nc(c(O)c(C(O)=O)c2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H14ClNO3/c1-9-7-10(2)15-13(8-9)14(18(22)23)17(21)16(20-15)11-3-5-12(19)6-4-11/h3-8,21H,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant DHOD expressed in Escherichia coli				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50201920 (2-(4-chlorophenyl)-3-hydroxy-6,8-dimethylquinoline...) Show SMILES Cc1cc(C)c2nc(c(O)c(C(O)=O)c2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H14ClNO3/c1-9-7-10(2)15-13(8-9)14(18(22)23)17(21)16(20-15)11-3-5-12(19)6-4-11/h3-8,21H,1-2H3,(H,22,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of P-selectin-mediated adhesion of HL60 cells				J Med Chem 50: 21-39 (2007) Article DOI: 10.1021/jm0602256 BindingDB Entry DOI: 10.7270/Q2Z60PVV
					More data for this Ligand-Target Pair