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SMILES: Cc1ccc2c(C(O)=O)c(O)c(nc2c1C)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=XIAKWAGZUGXLJL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201944   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P-selectin glycoprotein ligand 1


(Homo sapiens (Human))		BDBM50201944
PNG
(3-hydroxy-7,8-dimethyl-2-(3-(trifluoromethoxy)phen...)
Show SMILES Cc1ccc2c(C(O)=O)c(O)c(nc2c1C)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C19H14F3NO4/c1-9-6-7-13-14(18(25)26)17(24)16(23-15(13)10(9)2)11-4-3-5-12(8-11)27-19(20,21)22/h3-8,24H,1-2H3,(H,25,26)
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Article
PubMed
n/an/a 2.00E+5n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of P-selectin-mediated adhesion of HL60 cells

J Med Chem 50: 21-39 (2007)


Article DOI: 10.1021/jm0602256
BindingDB Entry DOI: 10.7270/Q2Z60PVV
More data for this
Ligand-Target Pair