BDBM50201999 CHEMBL3925939

SMILES: ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)c1ccc2cccc(F)c2n1

InChI Key: InChIKey=KSEOXVVKQGWKOD-VQHVLOKHSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50201999 (CHEMBL3925939) Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)c1ccc2cccc(F)c2n1 Show InChI InChI=1S/C18H13FN2O4S/c19-15-6-2-4-13-8-10-17(20-18(13)15)26(24,25)14-5-1-3-12(11-14)7-9-16(22)21-23/h1-11,23H,(H,21,22)/b9-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of His-tagged full length recombinant human HDAC8 expressed in baculovirus expression system assessed as release of 7-amino-4-methylcoumar...				Eur J Med Chem 122: 92-101 (2016) Article DOI: 10.1016/j.ejmech.2016.06.023 BindingDB Entry DOI: 10.7270/Q2J38VJ5
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50201999 (CHEMBL3925939) Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)c1ccc2cccc(F)c2n1 Show InChI InChI=1S/C18H13FN2O4S/c19-15-6-2-4-13-8-10-17(20-18(13)15)26(24,25)14-5-1-3-12(11-14)7-9-16(22)21-23/h1-11,23H,(H,21,22)/b9-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length recombinant human HDAC6 expressed in baculovirus expression system assessed as release of 7-amino-4-methylcoumarin by fluor...				Eur J Med Chem 122: 92-101 (2016) Article DOI: 10.1016/j.ejmech.2016.06.023 BindingDB Entry DOI: 10.7270/Q2J38VJ5
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50201999 (CHEMBL3925939) Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)c1ccc2cccc(F)c2n1 Show InChI InChI=1S/C18H13FN2O4S/c19-15-6-2-4-13-8-10-17(20-18(13)15)26(24,25)14-5-1-3-12(11-14)7-9-16(22)21-23/h1-11,23H,(H,21,22)/b9-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of full length recombinant human HDAC2 expressed in baculovirus expression system assessed as release of 7-amino-4-methylcoumarin by fluor...				Eur J Med Chem 122: 92-101 (2016) Article DOI: 10.1016/j.ejmech.2016.06.023 BindingDB Entry DOI: 10.7270/Q2J38VJ5
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50201999 (CHEMBL3925939) Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)c1ccc2cccc(F)c2n1 Show InChI InChI=1S/C18H13FN2O4S/c19-15-6-2-4-13-8-10-17(20-18(13)15)26(24,25)14-5-1-3-12(11-14)7-9-16(22)21-23/h1-11,23H,(H,21,22)/b9-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of C-terminal His/FLAG-tagged full length recombinant human HDAC1 expressed in baculovirus expression system assessed as release of 7-amin...				Eur J Med Chem 122: 92-101 (2016) Article DOI: 10.1016/j.ejmech.2016.06.023 BindingDB Entry DOI: 10.7270/Q2J38VJ5
					More data for this Ligand-Target Pair