BDBM50202209 CHEMBL389234::bis(7-methoxybenzo[b]furan-2-yl)methanone

SMILES: COc1cccc2cc(oc12)C(=O)c1cc2cccc(OC)c2o1

InChI Key: InChIKey=NJKZFKQLDOVFGO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50202209 (CHEMBL389234 | bis(7-methoxybenzo[b]furan-2-yl)met...) Show SMILES COc1cccc2cc(oc12)C(=O)c1cc2cccc(OC)c2o1 Show InChI InChI=1S/C19H14O5/c1-21-13-7-3-5-11-9-15(23-18(11)13)17(20)16-10-12-6-4-8-14(22-2)19(12)24-16/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous FLT3 autophosphorylation in EOL1 cells				Bioorg Med Chem 15: 2187-97 (2007) Article DOI: 10.1016/j.bmc.2006.12.011 BindingDB Entry DOI: 10.7270/Q2F47NT9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50202209 (CHEMBL389234 | bis(7-methoxybenzo[b]furan-2-yl)met...) Show SMILES COc1cccc2cc(oc12)C(=O)c1cc2cccc(OC)c2o1 Show InChI InChI=1S/C19H14O5/c1-21-13-7-3-5-11-9-15(23-18(11)13)17(20)16-10-12-6-4-8-14(22-2)19(12)24-16/h3-10H,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFRbeta autophosphorylation in Swiss 3T3 fibroblasts				Bioorg Med Chem 15: 2187-97 (2007) Article DOI: 10.1016/j.bmc.2006.12.011 BindingDB Entry DOI: 10.7270/Q2F47NT9
					More data for this Ligand-Target Pair