BDBM50202211 CHEMBL225827::bis(6-hydroxybenzo[b]furan-2-yl)methanone

SMILES: Oc1ccc2cc(oc2c1)C(=O)c1cc2ccc(O)cc2o1

InChI Key: InChIKey=RMZPEAFTFQMIEY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50202211 (CHEMBL225827 | bis(6-hydroxybenzo[b]furan-2-yl)met...) Show SMILES Oc1ccc2cc(oc2c1)C(=O)c1cc2ccc(O)cc2o1 Show InChI InChI=1S/C17H10O5/c18-11-3-1-9-5-15(21-13(9)7-11)17(20)16-6-10-2-4-12(19)8-14(10)22-16/h1-8,18-19H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFRbeta autophosphorylation in Swiss 3T3 fibroblasts				Bioorg Med Chem 15: 2187-97 (2007) Article DOI: 10.1016/j.bmc.2006.12.011 BindingDB Entry DOI: 10.7270/Q2F47NT9
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50202211 (CHEMBL225827 | bis(6-hydroxybenzo[b]furan-2-yl)met...) Show SMILES Oc1ccc2cc(oc2c1)C(=O)c1cc2ccc(O)cc2o1 Show InChI InChI=1S/C17H10O5/c18-11-3-1-9-5-15(21-13(9)7-11)17(20)16-6-10-2-4-12(19)8-14(10)22-16/h1-8,18-19H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous FLT3 autophosphorylation in EOL1 cells				Bioorg Med Chem 15: 2187-97 (2007) Article DOI: 10.1016/j.bmc.2006.12.011 BindingDB Entry DOI: 10.7270/Q2F47NT9
					More data for this Ligand-Target Pair