BDBM50202272 2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoic acid::CHEMBL437577

SMILES: CCC\C(=C1\SC(=S)N([C@@H](Cc2ccccc2)C(O)=O)C1=O)c1ccccc1

InChI Key: InChIKey=KAOXISQJUWHXIJ-VZCCSQPZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50202272 (2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES CCC\C(=C1\SC(=S)N([C@@H](Cc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C22H21NO3S2/c1-2-9-17(16-12-7-4-8-13-16)19-20(24)23(22(27)28-19)18(21(25)26)14-15-10-5-3-6-11-15/h3-8,10-13,18H,2,9,14H2,1H3,(H,25,26)/b19-17-/t18-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair
BCL-W (Homo sapiens (Human))	BDBM50202272 (2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES CCC\C(=C1\SC(=S)N([C@@H](Cc2ccccc2)C(O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C22H21NO3S2/c1-2-9-17(16-12-7-4-8-13-16)19-20(24)23(22(27)28-19)18(21(25)26)14-15-10-5-3-6-11-15/h3-8,10-13,18H,2,9,14H2,1H3,(H,25,26)/b19-17-/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair