BDBM50202278 2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylthiobutanoic acid::CHEMBL241897

SMILES: CSCC[C@H](N1C(=S)S\C(=C/c2ccc(Br)cc2)C1=O)C(O)=O

InChI Key: InChIKey=MGWJFVUZXCZWFY-LCFDYFRESA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50202278 (2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES CSCC[C@H](N1C(=S)S\C(=C/c2ccc(Br)cc2)C1=O)C(O)=O Show InChI InChI=1S/C15H14BrNO3S3/c1-22-7-6-11(14(19)20)17-13(18)12(23-15(17)21)8-9-2-4-10(16)5-3-9/h2-5,8,11H,6-7H2,1H3,(H,19,20)/b12-8-/t11-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.96E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair
BCL-W (Homo sapiens (Human))	BDBM50202278 (2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES CSCC[C@H](N1C(=S)S\C(=C/c2ccc(Br)cc2)C1=O)C(O)=O Show InChI InChI=1S/C15H14BrNO3S3/c1-22-7-6-11(14(19)20)17-13(18)12(23-15(17)21)8-9-2-4-10(16)5-3-9/h2-5,8,11H,6-7H2,1H3,(H,19,20)/b12-8-/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair