BDBM50202395 (RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine::CHEMBL218847

SMILES: CCCC(C1CCCCN1)c1ccc(Cl)cc1

InChI Key: InChIKey=OICPVJMMZDEJMO-UHFFFAOYSA-N

Data: 6 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50202395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human DAT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human NET expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human DAT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human NET expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human SERT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 from human SERT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake into human NET expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake into human NET expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at human DAT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50202395 ((RS/SR)-2-[1-(4-chlorophenyl)butyl]piperidine | CH...) Show SMILES CCCC(C1CCCCN1)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H22ClN/c1-2-5-14(15-6-3-4-11-17-15)12-7-9-13(16)10-8-12/h7-10,14-15,17H,2-6,11H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts College of Pharmacy and Health Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at human DAT expressing HEK293 cells				J Med Chem 50: 219-32 (2007) Article DOI: 10.1021/jm0608614 BindingDB Entry DOI: 10.7270/Q2PN96F3
					More data for this Ligand-Target Pair