BDBM50202413 CHEMBL384893::methyl 4'-{[({1-[(difluoroacetyl)amino]cyclopropyl}carbonyl)-amino]methyl}-3,3'-difluoro-1,1'-biphenyl-2-carboxylate

SMILES: COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)C2(CC2)NC(=O)C(F)F)c(F)c1

InChI Key: InChIKey=GGDMTXGFPWHKEJ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50202413 (CHEMBL384893 | methyl 4'-{[({1-[(difluoroacetyl)am...) Show SMILES COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)C2(CC2)NC(=O)C(F)F)c(F)c1 Show InChI InChI=1S/C21H18F4N2O4/c1-31-19(29)16-13(3-2-4-14(16)22)11-5-6-12(15(23)9-11)10-26-20(30)21(7-8-21)27-18(28)17(24)25/h2-6,9,17H,7-8,10H2,1H3,(H,26,30)(H,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cells				J Med Chem 50: 272-82 (2007) Article DOI: 10.1021/jm061094b BindingDB Entry DOI: 10.7270/Q2X63MMQ
					More data for this Ligand-Target Pair
BDKRB2 (Homo sapiens (Human))	BDBM50202413 (CHEMBL384893 | methyl 4'-{[({1-[(difluoroacetyl)am...) Show SMILES COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)C2(CC2)NC(=O)C(F)F)c(F)c1 Show InChI InChI=1S/C21H18F4N2O4/c1-31-19(29)16-13(3-2-4-14(16)22)11-5-6-12(15(23)9-11)10-26-20(30)21(7-8-21)27-18(28)17(24)25/h2-6,9,17H,7-8,10H2,1H3,(H,26,30)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human bradykinin B2 receptor				J Med Chem 50: 272-82 (2007) Article DOI: 10.1021/jm061094b BindingDB Entry DOI: 10.7270/Q2X63MMQ
					More data for this Ligand-Target Pair