BDBM50202430 CHEMBL220978::N-{(1R)-1-[3,3'-difluoro-2'-(1-methyl-1H-tetraazol-5-yl)-1,1'-biphenyl-4-yl]ethyl}-1-[(trifluoroacetyl)amino]cyclopropanecarboxamide

SMILES: C[C@@H](NC(=O)C1(CC1)NC(=O)C(F)(F)F)c1ccc(cc1F)-c1cccc(F)c1-c1nnnn1C

InChI Key: InChIKey=FJHPRKDIKUBEPH-LLVKDONJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B1 bradykinin receptor (Homo sapiens (Human))	BDBM50202430 (CHEMBL220978 | N-{(1R)-1-[3,3'-difluoro-2'-(1-meth...) Show SMILES C[C@@H](NC(=O)C1(CC1)NC(=O)C(F)(F)F)c1ccc(cc1F)-c1cccc(F)c1-c1nnnn1C |r,wU:1.0,(-6.38,-42.46,;-6.38,-40.92,;-7.71,-40.15,;-9.05,-40.92,;-9.05,-42.46,;-10.38,-40.15,;-11.17,-41.48,;-11.93,-40.14,;-10.38,-38.61,;-9.05,-37.84,;-7.71,-38.61,;-9.05,-36.31,;-9.06,-34.77,;-7.52,-36.3,;-10.58,-36.32,;-5.04,-40.14,;-5.05,-38.61,;-3.72,-37.84,;-2.38,-38.61,;-2.38,-40.15,;-3.71,-40.92,;-3.72,-42.46,;-1.05,-37.84,;.29,-38.61,;1.61,-37.84,;1.61,-36.3,;.27,-35.53,;.27,-33.99,;-1.06,-36.31,;-2.39,-35.56,;-3.77,-36.2,;-4.82,-35.08,;-4.07,-33.74,;-2.56,-34.04,;-1.43,-33,)| Show InChI InChI=1S/C22H19F5N6O2/c1-11(28-19(34)21(8-9-21)29-20(35)22(25,26)27)13-7-6-12(10-16(13)24)14-4-3-5-15(23)17(14)18-30-31-32-33(18)2/h3-7,10-11H,8-9H2,1-2H3,(H,28,34)(H,29,35)/t11-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cells				J Med Chem 50: 272-82 (2007) Article DOI: 10.1021/jm061094b BindingDB Entry DOI: 10.7270/Q2X63MMQ
					More data for this Ligand-Target Pair