BDBM50202457 CHEMBL3263909

SMILES: COc1cccc(Cn2cc(\C=C3/Oc4cc(O)cc(O)c4C3=O)c3ccccc23)c1

InChI Key: InChIKey=QAHCNCVNSLMQAR-RMORIDSASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Multidrug resistance-associated protein 2 (MRP2) (Homo sapiens (Human))	BDBM50202457 (CHEMBL3263909) Show SMILES COc1cccc(Cn2cc(\C=C3/Oc4cc(O)cc(O)c4C3=O)c3ccccc23)c1 Show InChI InChI=1S/C25H19NO5/c1-30-18-6-4-5-15(9-18)13-26-14-16(19-7-2-3-8-20(19)26)10-23-25(29)24-21(28)11-17(27)12-22(24)31-23/h2-12,14,27-28H,13H2,1H3/b23-10-	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
BMSSI UMR 5086 CNRS/Universit£ Lyon 1 Curated by ChEMBL					Assay Description Inhibition of ABCC2 (unknown origin) expressed in MDCK2 cells assessed as inhibition of calcein-AM efflux measured after 30 mins in presence of ABCB1...				Eur J Med Chem 122: 408-418 (2016) Article DOI: 10.1016/j.ejmech.2016.06.039 BindingDB Entry DOI: 10.7270/Q2RN39TM
					More data for this Ligand-Target Pair