BDBM50202472 CHEMBL3927809

SMILES: CC(C)Cc1ccc(cc1)C(C)c1nc2cc(OCC=C)ccc2n1Cc1ccccc1C(F)(F)F

InChI Key: InChIKey=KHBCORYYYNXHEB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202472   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50202472 (CHEMBL3927809) Show SMILES CC(C)Cc1ccc(cc1)C(C)c1nc2cc(OCC=C)ccc2n1Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C30H31F3N2O/c1-5-16-36-25-14-15-28-27(18-25)34-29(21(4)23-12-10-22(11-13-23)17-20(2)3)35(28)19-24-8-6-7-9-26(24)30(31,32)33/h5-15,18,20-21H,1,16-17,19H2,2-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Gazi University Curated by ChEMBL					Assay Description Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...				Eur J Med Chem 122: 510-519 (2016) Article DOI: 10.1016/j.ejmech.2016.07.004 BindingDB Entry DOI: 10.7270/Q2H41TCW
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