BDBM50202475 CHEMBL3983042

SMILES: CC(C)Cc1ccc(cc1)C(C)c1nc2cc(OCc3ccccc3C#N)ccc2n1Cc1ccccc1Cl

InChI Key: InChIKey=DUUHCBSNNSXUGO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-lipoxygenase/FLAP (Homo sapiens (Human))	BDBM50202475 (CHEMBL3983042) Show SMILES CC(C)Cc1ccc(cc1)C(C)c1nc2cc(OCc3ccccc3C#N)ccc2n1Cc1ccccc1Cl Show InChI InChI=1S/C34H32ClN3O/c1-23(2)18-25-12-14-26(15-13-25)24(3)34-37-32-19-30(39-22-29-10-5-4-8-27(29)20-36)16-17-33(32)38(34)21-28-9-6-7-11-31(28)35/h4-17,19,23-24H,18,21-22H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Gazi University Curated by ChEMBL					Assay Description Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...				Eur J Med Chem 122: 510-519 (2016) Article DOI: 10.1016/j.ejmech.2016.07.004 BindingDB Entry DOI: 10.7270/Q2H41TCW
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