BDBM50203002 3-(2-hydroxy-4-methylphenylamino)-4-(phenylamino)cyclobut-3-ene-1,2-dione::CHEMBL392181

SMILES: Cc1ccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c(O)c1

InChI Key: InChIKey=CGFCJFIIBAQJSX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50203002 (3-(2-hydroxy-4-methylphenylamino)-4-(phenylamino)c...) Show SMILES Cc1ccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c(O)c1 Show InChI InChI=1S/C17H14N2O3/c1-10-7-8-12(13(20)9-10)19-15-14(16(21)17(15)22)18-11-5-3-2-4-6-11/h2-9,18-20H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 17: 1713-7 (2007) Article DOI: 10.1016/j.bmcl.2006.12.067 BindingDB Entry DOI: 10.7270/Q2Z320GC
					More data for this Ligand-Target Pair