BDBM50203027 3-[2-hydroxy-3-(4-methyl-[1,4]diazepane-1-carbonyl)-phenylamino]-4-phenylamino-cyclobut-3-ene-1,2-dione trifluoro-acetic acid salt::CHEMBL240458

SMILES: CN1CCCN(CC1)C(=O)c1cccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O

InChI Key: InChIKey=DGIMTYUCVVGWCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50203027 (3-[2-hydroxy-3-(4-methyl-[1,4]diazepane-1-carbonyl...) Show SMILES CN1CCCN(CC1)C(=O)c1cccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O Show InChI InChI=1S/C23H24N4O4/c1-26-11-6-12-27(14-13-26)23(31)16-9-5-10-17(20(16)28)25-19-18(21(29)22(19)30)24-15-7-3-2-4-8-15/h2-5,7-10,24-25,28H,6,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human recombinant CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 17: 1713-7 (2007) Article DOI: 10.1016/j.bmcl.2006.12.067 BindingDB Entry DOI: 10.7270/Q2Z320GC
					More data for this Ligand-Target Pair