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BDBM50203730 CHEMBL3902070

SMILES: FC1(F)CCN(CC1Oc1ccc2ccccc2n1)C(=O)c1cccc2nccn12

InChI Key: InChIKey=IKWKSHFODDVFDP-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203730   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))		BDBM50203730
PNG
(CHEMBL3902070)
Show SMILES FC1(F)CCN(CC1Oc1ccc2ccccc2n1)C(=O)c1cccc2nccn12
Show InChI InChI=1S/C22H18F2N4O2/c23-22(24)10-12-27(21(29)17-6-3-7-19-25-11-13-28(17)19)14-18(22)30-20-9-8-15-4-1-2-5-16(15)26-20/h1-9,11,13,18H,10,12,14H2
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Similars
Article
PubMed
>3.33E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of (2S)-N-(2-pyrrol-1-ylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from human OX2 recep...

Bioorg Med Chem Lett 26: 5809-5814 (2016)


Article DOI: 10.1016/j.bmcl.2016.10.019
BindingDB Entry DOI: 10.7270/Q2MS3VRG
More data for this
Ligand-Target Pair