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SMILES: FC1(F)CCN(CC1Oc1nccc2ccccc12)C(=O)c1ccccc1-n1nccn1

InChI Key: InChIKey=RCRZQMQCOBKRAY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203736   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))		BDBM50203736
PNG
(CHEMBL3915136)
Show SMILES FC1(F)CCN(CC1Oc1nccc2ccccc12)C(=O)c1ccccc1-n1nccn1
Show InChI InChI=1S/C23H19F2N5O2/c24-23(25)10-14-29(22(31)18-7-3-4-8-19(18)30-27-12-13-28-30)15-20(23)32-21-17-6-2-1-5-16(17)9-11-26-21/h1-9,11-13,20H,10,14-15H2
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Article
PubMed
 2.80n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of (2S)-N-(2-pyrrol-1-ylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from human OX2 recep...

Bioorg Med Chem Lett 26: 5809-5814 (2016)


Article DOI: 10.1016/j.bmcl.2016.10.019
BindingDB Entry DOI: 10.7270/Q2MS3VRG
More data for this
Ligand-Target Pair