BDBM50203757 CHEMBL3897218

SMILES: FC1(F)CCN(CC1Oc1cnc2ccccc2n1)C(=O)c1ccccc1-n1nccn1

InChI Key: InChIKey=XDXUAHLLFAFWCF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50203757 (CHEMBL3897218) Show SMILES FC1(F)CCN(CC1Oc1cnc2ccccc2n1)C(=O)c1ccccc1-n1nccn1 Show InChI InChI=1S/C22H18F2N6O2/c23-22(24)9-12-29(21(31)15-5-1-4-8-18(15)30-26-10-11-27-30)14-19(22)32-20-13-25-16-6-2-3-7-17(16)28-20/h1-8,10-11,13,19H,9,12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of (2S)-N-(2-pyrrol-1-ylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from human OX2 recep...				Bioorg Med Chem Lett 26: 5809-5814 (2016) Article DOI: 10.1016/j.bmcl.2016.10.019 BindingDB Entry DOI: 10.7270/Q2MS3VRG
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