BDBM50203835 CHEMBL221638::N-[4-({[1-(5-aminopentanoyl)piperidin-4-yl]amino}sulfonyl)-1-naphthyl]-2-methyl-benzamide

SMILES: Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCCCN

InChI Key: InChIKey=SAAGNUZHTSXRHL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50203835 (CHEMBL221638 | N-[4-({[1-(5-aminopentanoyl)piperid...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)CCCCN Show InChI InChI=1S/C28H34N4O4S/c1-20-8-2-3-9-22(20)28(34)30-25-13-14-26(24-11-5-4-10-23(24)25)37(35,36)31-21-15-18-32(19-16-21)27(33)12-6-7-17-29/h2-5,8-11,13-14,21,31H,6-7,12,15-19,29H2,1H3,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	199	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assay				J Med Chem 50: 566-84 (2007) Article DOI: 10.1021/jm061118e BindingDB Entry DOI: 10.7270/Q24J0DSN
					More data for this Ligand-Target Pair