BDBM50203852 CHEMBL221639::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-3-fluorobenzamide

SMILES: CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccc(F)c2)c2ccccc12

InChI Key: InChIKey=IWDRXZJZYMGZJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50203852 (CHEMBL221639 | N-(4-{[(1-butyrylpiperidin-4-yl)ami...) Show SMILES CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccc(F)c2)c2ccccc12 Show InChI InChI=1S/C26H28FN3O4S/c1-2-6-25(31)30-15-13-20(14-16-30)29-35(33,34)24-12-11-23(21-9-3-4-10-22(21)24)28-26(32)18-7-5-8-19(27)17-18/h3-5,7-12,17,20,29H,2,6,13-16H2,1H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...				J Med Chem 50: 566-84 (2007) Article DOI: 10.1021/jm061118e BindingDB Entry DOI: 10.7270/Q24J0DSN
					More data for this Ligand-Target Pair