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SMILES: CC1CN(CCCOC(=O)N2CCC(CC2)NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC(C)O1

InChI Key: InChIKey=RCSMPRZXADOTLA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203893   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 8


(Homo sapiens (Human))		BDBM50203893
PNG
(3-(2,6-dimethylmorpholin-4-yl)propyl-4-[({4-[(2-me...)
Show SMILES CC1CN(CCCOC(=O)N2CCC(CC2)NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC(C)O1
Show InChI InChI=1S/C33H42N4O6S/c1-23-9-4-5-10-27(23)32(38)34-30-13-14-31(29-12-7-6-11-28(29)30)44(40,41)35-26-15-18-37(19-16-26)33(39)42-20-8-17-36-21-24(2)43-25(3)22-36/h4-7,9-14,24-26,35H,8,15-22H2,1-3H3,(H,34,38)
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UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 19.6n/an/an/an/an/an/a



Millennium Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...

J Med Chem 50: 566-84 (2007)


Article DOI: 10.1021/jm061118e
BindingDB Entry DOI: 10.7270/Q24J0DSN
More data for this
Ligand-Target Pair