BDBM50203899 4-tert-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)benzamide::CHEMBL218297

SMILES: CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)c2ccccc12

InChI Key: InChIKey=NFULGCSRYNEYAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203899   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50203899 (4-tert-butyl-N-(4-{[(1-butyrylpiperidin-4-yl)amino...) Show SMILES CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2ccc(cc2)C(C)(C)C)c2ccccc12 Show InChI InChI=1S/C30H37N3O4S/c1-5-8-28(34)33-19-17-23(18-20-33)32-38(36,37)27-16-15-26(24-9-6-7-10-25(24)27)31-29(35)21-11-13-22(14-12-21)30(2,3)4/h6-7,9-16,23,32H,5,8,17-20H2,1-4H3,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...				J Med Chem 50: 566-84 (2007) Article DOI: 10.1021/jm061118e BindingDB Entry DOI: 10.7270/Q24J0DSN
					More data for this Ligand-Target Pair