BDBM50203908 CHEMBL221790::N-(4-{[(1-butyrylpiperidin-4-yl)amino]sulfonyl}-1-naphthyl)-3-methylbenzamide

SMILES: CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccc(C)c2)c2ccccc12

InChI Key: InChIKey=QSNIDHPXWJGJKF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50203908 (CHEMBL221790 | N-(4-{[(1-butyrylpiperidin-4-yl)ami...) Show SMILES CCCC(=O)N1CCC(CC1)NS(=O)(=O)c1ccc(NC(=O)c2cccc(C)c2)c2ccccc12 Show InChI InChI=1S/C27H31N3O4S/c1-3-7-26(31)30-16-14-21(15-17-30)29-35(33,34)25-13-12-24(22-10-4-5-11-23(22)25)28-27(32)20-9-6-8-19(2)18-20/h4-6,8-13,18,21,29H,3,7,14-17H2,1-2H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...				J Med Chem 50: 566-84 (2007) Article DOI: 10.1021/jm061118e BindingDB Entry DOI: 10.7270/Q24J0DSN
					More data for this Ligand-Target Pair