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SMILES: Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)c1ccccc1

InChI Key: InChIKey=BGAJBPXTYAWRIL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203918   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 8


(Homo sapiens (Human))		BDBM50203918
PNG
(CHEMBL387451 | N-(4-{[(1-benzoylpiperidin-4-yl)ami...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C30H29N3O4S/c1-21-9-5-6-12-24(21)29(34)31-27-15-16-28(26-14-8-7-13-25(26)27)38(36,37)32-23-17-19-33(20-18-23)30(35)22-10-3-2-4-11-22/h2-16,23,32H,17-20H2,1H3,(H,31,34)
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Similars
Article
PubMed
 81.1n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assay

J Med Chem 50: 566-84 (2007)


Article DOI: 10.1021/jm061118e
BindingDB Entry DOI: 10.7270/Q24J0DSN
More data for this
Ligand-Target Pair