BDBM50203986 2,2',4,4',6'-pentahydroxychalcone::CHEMBL244249
SMILES: Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)c(O)c1
InChI Key: InChIKey=MDRJIGPMMMALHB-DUXPYHPUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50203986 (2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase | Bioorg Med Chem 15: 2396-402 (2007) Article DOI: 10.1016/j.bmc.2007.01.017 BindingDB Entry DOI: 10.7270/Q2R78DWH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50203986 (2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degC | Bioorg Med Chem 21: 2156-62 (2013) Article DOI: 10.1016/j.bmc.2012.12.054 BindingDB Entry DOI: 10.7270/Q28P63FB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50203986 (2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of mushroom tyrosinase | Bioorg Med Chem 15: 2396-402 (2007) Article DOI: 10.1016/j.bmc.2007.01.017 BindingDB Entry DOI: 10.7270/Q2R78DWH | |||||||||||
More data for this Ligand-Target Pair |