BDBM50203986 2,2',4,4',6'-pentahydroxychalcone::CHEMBL244249

SMILES: Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)c(O)c1

InChI Key: InChIKey=MDRJIGPMMMALHB-DUXPYHPUSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50203986 (2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249) Show SMILES Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)c(O)c1 Show InChI InChI=1S/C15H12O6/c16-9-3-1-8(12(19)5-9)2-4-11(18)15-13(20)6-10(17)7-14(15)21/h1-7,16-17,19-21H/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem 15: 2396-402 (2007) Article DOI: 10.1016/j.bmc.2007.01.017 BindingDB Entry DOI: 10.7270/Q2R78DWH
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50203986 (2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249) Show SMILES Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)c(O)c1 Show InChI InChI=1S/C15H12O6/c16-9-3-1-8(12(19)5-9)2-4-11(18)15-13(20)6-10(17)7-14(15)21/h1-7,16-17,19-21H/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degC				Bioorg Med Chem 21: 2156-62 (2013) Article DOI: 10.1016/j.bmc.2012.12.054 BindingDB Entry DOI: 10.7270/Q28P63FB
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50203986 (2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249) Show SMILES Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)c(O)c1 Show InChI InChI=1S/C15H12O6/c16-9-3-1-8(12(19)5-9)2-4-11(18)15-13(20)6-10(17)7-14(15)21/h1-7,16-17,19-21H/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem 15: 2396-402 (2007) Article DOI: 10.1016/j.bmc.2007.01.017 BindingDB Entry DOI: 10.7270/Q2R78DWH
					More data for this Ligand-Target Pair