BDBM50204283 CHEMBL3898579

SMILES: [H][C@@]12CN[C@H](CN1CCN(C2)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C

InChI Key: InChIKey=SDODBDMSHPFEKL-LAUBAEHRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50204283 (CHEMBL3898579) Show SMILES [H][C@@]12CN[C@H](CN1CCN(C2)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C |r| Show InChI InChI=1S/C24H26N8O3/c1-15-18(3-4-19-20(15)13-35-24(19)34)21-12-30-6-7-31(11-17(30)10-25-21)23(33)8-16-2-5-22(26-9-16)32-14-27-28-29-32/h2-5,9,14,17,21,25H,6-8,10-13H2,1H3/t17-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 35S-MK499 from human ERG expressed in HEK293 cell membranes				Bioorg Med Chem Lett 26: 5695-5702 (2016) Article DOI: 10.1016/j.bmcl.2016.10.064 BindingDB Entry DOI: 10.7270/Q2F191PS
					More data for this Ligand-Target Pair
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50204283 (CHEMBL3898579) Show SMILES [H][C@@]12CN[C@H](CN1CCN(C2)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C |r| Show InChI InChI=1S/C24H26N8O3/c1-15-18(3-4-19-20(15)13-35-24(19)34)21-12-30-6-7-31(11-17(30)10-25-21)23(33)8-16-2-5-22(26-9-16)32-14-27-28-29-32/h2-5,9,14,17,21,25H,6-8,10-13H2,1H3/t17-,21+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ROMK expressed in CHO cells after 6 mins at -70 mV holding potential by electrophysiology method				Bioorg Med Chem Lett 26: 5695-5702 (2016) Article DOI: 10.1016/j.bmcl.2016.10.064 BindingDB Entry DOI: 10.7270/Q2F191PS
					More data for this Ligand-Target Pair