BDBM50204413 (3R,4R)-N-hydroxy-4-(4-((3-methylquinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL392686

SMILES: Cc1cnc2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO

InChI Key: InChIKey=XKRVFVOPYXCFOD-RBBKRZOGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204413   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50204413 ((3R,4R)-N-hydroxy-4-(4-((3-methylquinolin-4-yl)met...) Show SMILES Cc1cnc2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO Show InChI InChI=1S/C24H25N3O4/c1-15-13-25-21-5-3-2-4-18(21)19(15)12-16-6-8-17(9-7-16)23(28)26-22-10-11-31-14-20(22)24(29)27-30/h2-9,13,20,22,30H,10-12,14H2,1H3,(H,26,28)(H,27,29)/t20-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of TACE in human whole blood				Bioorg Med Chem Lett 17: 1865-70 (2007) Article DOI: 10.1016/j.bmcl.2007.01.041 BindingDB Entry DOI: 10.7270/Q2KK9BF4
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM50204413 ((3R,4R)-N-hydroxy-4-(4-((3-methylquinolin-4-yl)met...) Show SMILES Cc1cnc2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO Show InChI InChI=1S/C24H25N3O4/c1-15-13-25-21-5-3-2-4-18(21)19(15)12-16-6-8-17(9-7-16)23(28)26-22-10-11-31-14-20(22)24(29)27-30/h2-9,13,20,22,30H,10-12,14H2,1H3,(H,26,28)(H,27,29)/t20-,22+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of pig TACE				Bioorg Med Chem Lett 17: 1865-70 (2007) Article DOI: 10.1016/j.bmcl.2007.01.041 BindingDB Entry DOI: 10.7270/Q2KK9BF4
					More data for this Ligand-Target Pair