BDBM50204575 6-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)-5-phenyl-N-(2-(piperazin-1-yl)ethyl)furo[2,3-d]pyrimidin-4-amine::CHEMBL248079

SMILES: CN1CCOc2cc(ccc12)-c1oc2ncnc(NCCN3CCNCC3)c2c1-c1ccccc1

InChI Key: InChIKey=SWTRMCZKDHCOOZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50204575 (6-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-y...) Show SMILES CN1CCOc2cc(ccc12)-c1oc2ncnc(NCCN3CCNCC3)c2c1-c1ccccc1 Show InChI InChI=1S/C27H30N6O2/c1-32-15-16-34-22-17-20(7-8-21(22)32)25-23(19-5-3-2-4-6-19)24-26(30-18-31-27(24)35-25)29-11-14-33-12-9-28-10-13-33/h2-8,17-18,28H,9-16H2,1H3,(H,29,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50204575 (6-(4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-y...) Show SMILES CN1CCOc2cc(ccc12)-c1oc2ncnc(NCCN3CCNCC3)c2c1-c1ccccc1 Show InChI InChI=1S/C27H30N6O2/c1-32-15-16-34-22-17-20(7-8-21(22)32)25-23(19-5-3-2-4-6-19)24-26(30-18-31-27(24)35-25)29-11-14-33-12-9-28-10-13-33/h2-8,17-18,28H,9-16H2,1H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Ack1				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair