BDBM50204585 (S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine::CHEMBL247480

SMILES: C(CN1CCCC1)Oc1ccc(cc1)-c1oc2ncnc(NC[C@@H]3CCCO3)c2c1-c1ccccc1

InChI Key: InChIKey=YSWLNXFQMMFDFG-DEOSSOPVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50204585 ((S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)pheny...) Show SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1oc2ncnc(NC[C@@H]3CCCO3)c2c1-c1ccccc1 Show InChI InChI=1S/C29H32N4O3/c1-2-7-21(8-3-1)25-26-28(30-19-24-9-6-17-34-24)31-20-32-29(26)36-27(25)22-10-12-23(13-11-22)35-18-16-33-14-4-5-15-33/h1-3,7-8,10-13,20,24H,4-6,9,14-19H2,(H,30,31,32)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Ack1				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50204585 ((S)-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)pheny...) Show SMILES C(CN1CCCC1)Oc1ccc(cc1)-c1oc2ncnc(NC[C@@H]3CCCO3)c2c1-c1ccccc1 Show InChI InChI=1S/C29H32N4O3/c1-2-7-21(8-3-1)25-26-28(30-19-24-9-6-17-34-24)31-20-32-29(26)36-27(25)22-10-12-23(13-11-22)35-18-16-33-14-4-5-15-33/h1-3,7-8,10-13,20,24H,4-6,9,14-19H2,(H,30,31,32)/t24-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair