BDBM50204591 5-phenyl-N-(2-(piperidin-4-yl)ethyl)-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)furo[2,3-d]pyrimidin-4-amine::CHEMBL247469

SMILES: C(CC1CCNCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1

InChI Key: InChIKey=PNGBKTYRDRRBHW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50204591 (5-phenyl-N-(2-(piperidin-4-yl)ethyl)-6-(4-(2-(pyrr...) Show SMILES C(CC1CCNCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C31H37N5O2/c1-2-6-24(7-3-1)27-28-30(33-17-14-23-12-15-32-16-13-23)34-22-35-31(28)38-29(27)25-8-10-26(11-9-25)37-21-20-36-18-4-5-19-36/h1-3,6-11,22-23,32H,4-5,12-21H2,(H,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Ack1				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50204591 (5-phenyl-N-(2-(piperidin-4-yl)ethyl)-6-(4-(2-(pyrr...) Show SMILES C(CC1CCNCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C31H37N5O2/c1-2-6-24(7-3-1)27-28-30(33-17-14-23-12-15-32-16-13-23)34-22-35-31(28)38-29(27)25-8-10-26(11-9-25)37-21-20-36-18-4-5-19-36/h1-3,6-11,22-23,32H,4-5,12-21H2,(H,33,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair