null

SMILES: O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1

InChI Key: InChIKey=IWTNZBURNLPQET-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50204786 (1-phenyl-8-thiophen-3-ylmethyl-1,3,8-triaza-spiro[...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1 Show InChI InChI=1S/C18H21N3OS/c22-17-18(21(14-19-17)16-4-2-1-3-5-16)7-9-20(10-8-18)12-15-6-11-23-13-15/h1-6,11,13H,7-10,12,14H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204786 (1-phenyl-8-thiophen-3-ylmethyl-1,3,8-triaza-spiro[...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1 Show InChI InChI=1S/C18H21N3OS/c22-17-18(21(14-19-17)16-4-2-1-3-5-16)7-9-20(10-8-18)12-15-6-11-23-13-15/h1-6,11,13H,7-10,12,14H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204786 (1-phenyl-8-thiophen-3-ylmethyl-1,3,8-triaza-spiro[...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1 Show InChI InChI=1S/C18H21N3OS/c22-17-18(21(14-19-17)16-4-2-1-3-5-16)7-9-20(10-8-18)12-15-6-11-23-13-15/h1-6,11,13H,7-10,12,14H2,(H,19,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50204786 (1-phenyl-8-thiophen-3-ylmethyl-1,3,8-triaza-spiro[...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1 Show InChI InChI=1S/C18H21N3OS/c22-17-18(21(14-19-17)16-4-2-1-3-5-16)7-9-20(10-8-18)12-15-6-11-23-13-15/h1-6,11,13H,7-10,12,14H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair