BDBM50205148 CHEMBL3938747

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5Cl)c(=O)n4C4CC4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key: InChIKey=PDSCJCPVXJVZGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50205148 (CHEMBL3938747) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5Cl)c(=O)n4C4CC4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H37ClFN7O5/c1-42-15-17-43(18-16-42)14-5-19-49-33-22-28-25(21-32(33)48-2)30(12-13-39-28)50-31-11-8-23(20-27(31)38)40-35(46)34-41-45(29-7-4-3-6-26(29)37)36(47)44(34)24-9-10-24/h3-4,6-8,11-13,20-22,24H,5,9-10,14-19H2,1-2H3,(H,40,46)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin) using poly(Glu, Tyr)4:1 as substrate after 30 mins by HTRF assay				Eur J Med Chem 123: 431-446 (2016) Article DOI: 10.1016/j.ejmech.2016.07.059 BindingDB Entry DOI: 10.7270/Q2KK9DR0
					More data for this Ligand-Target Pair