BDBM50205307 CHEMBL412742::d[Cha4,Dab8]VP
SMILES: NCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSCCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC2CCCCC2)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
InChI Key: InChIKey=DPVYQFBOSXXNLG-CXWHUAPYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Vasopressin receptor (RAT) | BDBM50205307 (CHEMBL412742 | d[Cha4,Dab8]VP) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cells | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (RAT) | BDBM50205307 (CHEMBL412742 | d[Cha4,Dab8]VP) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from rat OT receptor expressed in CHO cells | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 Receptor (Rattus norvegicus (Rat)) | BDBM50205307 (CHEMBL412742 | d[Cha4,Dab8]VP) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from vasopressin V2 receptor in rat kidney membranes | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AVPR1A (RAT) | BDBM50205307 (CHEMBL412742 | d[Cha4,Dab8]VP) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from vasopressin V1a receptor in rat liver membrane | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50205307 (CHEMBL412742 | d[Cha4,Dab8]VP) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 447 | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Activity at OT receptor assessed as oxytocic activity in absence of magnesium | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair |