BDBM50205309 CHEMBL412972::d[Leu4,Lys8]VP
SMILES: CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)NCC(N)=O
InChI Key: InChIKey=QGZMLGLFLYCDQT-PEAOEFARSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin receptor (RAT) | BDBM50205309 (CHEMBL412972 | d[Leu4,Lys8]VP) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from rat vasopressin V1b receptor expressed in At-T20 cells | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (RAT) | BDBM50205309 (CHEMBL412972 | d[Leu4,Lys8]VP) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from rat OT receptor expressed in CHO cells | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 Receptor (Rattus norvegicus (Rat)) | BDBM50205309 (CHEMBL412972 | d[Leu4,Lys8]VP) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from vasopressin V2 receptor in rat kidney membranes | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AVPR1A (RAT) | BDBM50205309 (CHEMBL412972 | d[Leu4,Lys8]VP) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Displacement of [3H]AVP from vasopressin V1a receptor in rat liver membrane | J Med Chem 50: 835-47 (2007) Article DOI: 10.1021/jm060928n BindingDB Entry DOI: 10.7270/Q2G161NH | |||||||||||
More data for this Ligand-Target Pair |