BDBM50205339 CHEMBL3939457

SMILES: CCOc1ccc(cc1)S(=O)(=O)Nc1ccc(NS(=O)(=O)c2ccc(OCC)cc2)c2ccccc12

InChI Key: InChIKey=GVQLOWNGYDYVQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50205339 (CHEMBL3939457) Show SMILES CCOc1ccc(cc1)S(=O)(=O)Nc1ccc(NS(=O)(=O)c2ccc(OCC)cc2)c2ccccc12 Show InChI InChI=1S/C26H26N2O6S2/c1-3-33-19-9-13-21(14-10-19)35(29,30)27-25-17-18-26(24-8-6-5-7-23(24)25)28-36(31,32)22-15-11-20(12-16-22)34-4-2/h5-18,27-28H,3-4H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Keio University Curated by ChEMBL					Assay Description Inhibition of recombinant GST-His-tagged Keap1-DC domain (321 to 609 residues) (unknown origin) expressed in Escherichia coli/FAM-labeled Nrf2 (unkno...				Bioorg Med Chem Lett 26: 5956-5959 (2016) Article DOI: 10.1016/j.bmcl.2016.10.083 BindingDB Entry DOI: 10.7270/Q2PC34CB
					More data for this Ligand-Target Pair