BDBM50205403 5-{2-[(2'3',4'-hydroxy-biphenyl-3-carbonyl)-amino]-phenyl}-thiophene-2-carboxylic acid::CHEMBL373592

SMILES: OC(=O)c1ccc(s1)-c1ccccc1NC(=O)c1cccc(c1)-c1ccc(O)c(O)c1O

InChI Key: InChIKey=UWEWOIYXLWDCAV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-selectin (Homo sapiens (Human))	BDBM50205403 (5-{2-[(2'3',4'-hydroxy-biphenyl-3-carbonyl)-amino]...) Show SMILES OC(=O)c1ccc(s1)-c1ccccc1NC(=O)c1cccc(c1)-c1ccc(O)c(O)c1O Show InChI InChI=1S/C24H17NO6S/c26-18-9-8-15(21(27)22(18)28)13-4-3-5-14(12-13)23(29)25-17-7-2-1-6-16(17)19-10-11-20(32-19)24(30)31/h1-12,26-28H,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Revotar Biopharmaceuticals AG Curated by ChEMBL					Assay Description Inhibition of human P-selectin after 2 hrs				J Med Chem 50: 1101-15 (2007) Article DOI: 10.1021/jm060536g BindingDB Entry DOI: 10.7270/Q2TB17Q6
					More data for this Ligand-Target Pair
L-selectin (Homo sapiens (Human))	BDBM50205403 (5-{2-[(2'3',4'-hydroxy-biphenyl-3-carbonyl)-amino]...) Show SMILES OC(=O)c1ccc(s1)-c1ccccc1NC(=O)c1cccc(c1)-c1ccc(O)c(O)c1O Show InChI InChI=1S/C24H17NO6S/c26-18-9-8-15(21(27)22(18)28)13-4-3-5-14(12-13)23(29)25-17-7-2-1-6-16(17)19-10-11-20(32-19)24(30)31/h1-12,26-28H,(H,25,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Revotar Biopharmaceuticals AG Curated by ChEMBL					Assay Description Inhibition of human L-selectin after 2 hrs				J Med Chem 50: 1101-15 (2007) Article DOI: 10.1021/jm060536g BindingDB Entry DOI: 10.7270/Q2TB17Q6
					More data for this Ligand-Target Pair
E-selectin (Homo sapiens (Human))	BDBM50205403 (5-{2-[(2'3',4'-hydroxy-biphenyl-3-carbonyl)-amino]...) Show SMILES OC(=O)c1ccc(s1)-c1ccccc1NC(=O)c1cccc(c1)-c1ccc(O)c(O)c1O Show InChI InChI=1S/C24H17NO6S/c26-18-9-8-15(21(27)22(18)28)13-4-3-5-14(12-13)23(29)25-17-7-2-1-6-16(17)19-10-11-20(32-19)24(30)31/h1-12,26-28H,(H,25,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Revotar Biopharmaceuticals AG Curated by ChEMBL					Assay Description Inhibition of human E-selectin after 2 hrs				J Med Chem 50: 1101-15 (2007) Article DOI: 10.1021/jm060536g BindingDB Entry DOI: 10.7270/Q2TB17Q6
					More data for this Ligand-Target Pair