BDBM50205609 CHEMBL3938207

SMILES: COc1ccc(cc1OC)C1=NN(CCCO)C(=O)CC(C)(C)C1

InChI Key: InChIKey=HRKLKBXBIGHLIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50205609 (CHEMBL3938207) Show SMILES COc1ccc(cc1OC)C1=NN(CCCO)C(=O)CC(C)(C)C1 |t:11| Show InChI InChI=1S/C18H26N2O4/c1-18(2)11-14(19-20(8-5-9-21)17(22)12-18)13-6-7-15(23-3)16(10-13)24-4/h6-7,10,21H,5,8-9,11-12H2,1-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assay				Bioorg Med Chem Lett 27: 24-29 (2017) Article DOI: 10.1016/j.bmcl.2016.11.040 BindingDB Entry DOI: 10.7270/Q21N8333
					More data for this Ligand-Target Pair