BDBM50205732 1-(3-diethylamino-propylamino)-3-methyl-2-(2-methyl-allyl)-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile::CHEMBL223686

SMILES: CCN(CC)CCCNc1c(CC(C)=C)c(C)c(C#N)c2nc3ccccc3n12

InChI Key: InChIKey=MTDJLYRNZKODDY-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50205732 (1-(3-diethylamino-propylamino)-3-methyl-2-(2-methy...) Show SMILES CCN(CC)CCCNc1c(CC(C)=C)c(C)c(C#N)c2nc3ccccc3n12 Show InChI InChI=1S/C24H31N5/c1-6-28(7-2)14-10-13-26-23-19(15-17(3)4)18(5)20(16-25)24-27-21-11-8-9-12-22(21)29(23)24/h8-9,11-12,26H,3,6-7,10,13-15H2,1-2,4-5H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 7175-LC1 Curated by ChEMBL					Assay Description Displacement of [125I]MIP1beta from CCR5 expressed in CHO-K1 cells				J Med Chem 50: 1294-303 (2007) Article DOI: 10.1021/jm061389p BindingDB Entry DOI: 10.7270/Q2KD1XK6
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50205732 (1-(3-diethylamino-propylamino)-3-methyl-2-(2-methy...) Show SMILES CCN(CC)CCCNc1c(CC(C)=C)c(C)c(C#N)c2nc3ccccc3n12 Show InChI InChI=1S/C24H31N5/c1-6-28(7-2)14-10-13-26-23-19(15-17(3)4)18(5)20(16-25)24-27-21-11-8-9-12-22(21)29(23)24/h8-9,11-12,26H,3,6-7,10,13-15H2,1-2,4-5H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
CNRS UMR 7175-LC1 Curated by ChEMBL					Assay Description Agonist activity at CCR5 expressed in CHO-K1 cells in aqeuorin based assay				J Med Chem 50: 1294-303 (2007) Article DOI: 10.1021/jm061389p BindingDB Entry DOI: 10.7270/Q2KD1XK6
					More data for this Ligand-Target Pair