BDBM50205820 CHEMBL3919135

SMILES: CN1Cc2cc(NC(=O)COc3cccc(c3)[C@@H](Nc3ccc4c(N)nccc4c3)C1=O)ccc2S(=O)(=O)C1CC1

InChI Key: InChIKey=NLGPCPOAOWXKGZ-MUUNZHRXSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50205820 (CHEMBL3919135) Show SMILES CN1Cc2cc(NC(=O)COc3cccc(c3)[C@@H](Nc3ccc4c(N)nccc4c3)C1=O)ccc2S(=O)(=O)C1CC1 |r| Show InChI InChI=1S/C30H29N5O5S/c1-35-16-20-14-21(6-10-26(20)41(38,39)24-7-8-24)33-27(36)17-40-23-4-2-3-19(15-23)28(30(35)37)34-22-5-9-25-18(13-22)11-12-32-29(25)31/h2-6,9-15,24,28,34H,7-8,16-17H2,1H3,(H2,31,32)(H,33,36)/t28-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human factor-7a/TF using S2288 as substrate measured after 60 mins at 25 degC				ACS Med Chem Lett 8: 67-72 (2017) Article DOI: 10.1021/acsmedchemlett.6b00375 BindingDB Entry DOI: 10.7270/Q20P120Q
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